AUDITORY LATERALITY IN DEPRESSION: RELATION TO CIRCADIAN PATTERNS.
Item
-
Title
-
AUDITORY LATERALITY IN DEPRESSION: RELATION TO CIRCADIAN PATTERNS.
-
Identifier
-
AAI8601624
-
identifier
-
8601624
-
Creator
-
BERGER-GROSS, PAUL.
-
Contributor
-
Gerard G
-
Date
-
1985
-
Language
-
English
-
Publisher
-
City University of New York.
-
Subject
-
Psychology, Clinical
-
Abstract
-
The purpose of this study was to investigate the relationships between measures of auditory laterality and circadian rhythm disturbance in depressives using monotic and dichotic click detection, dichotic consonant-vowel (CV) discrimination, Purdue Pegboard, and visual (letter and dot) matching tasks. Both ED and ND patients displayed morning dichotic click detection lateral asymmetries suggestive of right hemisphere dysfunction and a morning-to-evening shift in lateral asymmetry opposite in direction to that previously seen for normal subjects.;The abnormal lateral asymmetry for dichotic click detection in the morning was significantly correlated with EEG sleep characteristics (sleep latency, REM period latency, REM time) and ratings of diurnal variation on the Hamilton Depression Scale. ED and ND patients displayed the normal right ear advantage for dichotic CV's and there was no morning-to-evening shift in CV asymmetries.;There was also a significant lateral asymmetry for detecting monotic click stimuli in ED patients that was not correlated with dichotic click detection asymmetries. The ED patients displayed significantly poorer left ear as compared to right ear sensitivity in the morning, but not in the evening. The monotic detection finding again suggests the importance of cyclical mechanisms in abnormal perceptual asymmetries in depressives.;A right hand advantage seen on the Purdue Pegboard may also support a right hemisphere deficit hypothesis of depression, especially considering the significant correlation between faster left hand (right hemisphere) speed and lower (i.e. healthier) Hamilton Depression Scale scores. In the evening, faster visual matching speed, faster Purdue Pegboard placement, and decreased total (both ears) CV discrimination were correlated with reduced sleep efficiency. These relationships suggest overarousal in the evening, a circadian disturbance which may also affect the continuity of sleep.;This study suggests that some right hemisphere deficits seen in depressed patients fluctuate with time-of-day in a pattern which is the opposite of that previously observed in normal subjects. This abnormal circadian shift in asymmetries was related to disturbances of other cyclical phenomena such as sleep/wake patterns and diurnal mood changes. Symptom, sleep and endocrine variables provided the basis for preliminary speculation on the mechanism of such abnormal patterns of hemisphere efficiency in ED and ND patients. (Abstract shortened with permission of author.).
-
Type
-
dissertation
-
Source
-
PQT Legacy CUNY.xlsx
-
degree
-
Ph.D.
-
Program
-
Psychology
