Motor-evoked potentials elicited from pyramidal system stimulation in the rat.
Item
-
Title
-
Motor-evoked potentials elicited from pyramidal system stimulation in the rat.
-
Identifier
-
AAI9000063
-
identifier
-
9000063
-
Creator
-
Ryder, John.
-
Contributor
-
Adviser: Rosario Zappulla
-
Date
-
1989
-
Language
-
English
-
Publisher
-
City University of New York.
-
Subject
-
Biology, Animal Physiology
-
Abstract
-
This study examines the generators and pathways mediating spinal motor evoked potentials to transcortical stimulation in the rat. A series of experiments were performed to define the electrophysiologic activity that is elicited during focal, low intensity stimulation restricted to the motor cortex under various conditions. The results demonstrate a long latency response originating in the cortex and recordable from the thoracic spinal cord which is different from the short latency responses previously reported. The conduction velocity of this later response is that reported for the pyramidal tract in the rat. Further experiments confirm that the longer latency response depends upon activation of the pyramidal system in the motor cortex and travels through the pyramidal tract. The utility of the rat model and the implications of these results with respect to the motor system are discussed.
-
Type
-
dissertation
-
Source
-
PQT Legacy CUNY.xlsx
-
degree
-
Ph.D.
