The prediction of IQ and cognitive impairment in temporal lobe epilepsy: The findings of a multi-center study.
Item
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Title
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The prediction of IQ and cognitive impairment in temporal lobe epilepsy: The findings of a multi-center study.
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Identifier
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AAI9732984
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identifier
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9732984
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Creator
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Warmflash, Valerie Lynn.
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Contributor
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Adviser: Jeffrey Rosen
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Date
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1997
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Language
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English
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Publisher
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City University of New York.
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Subject
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Psychology, Cognitive | Psychology, Developmental
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Abstract
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The literature suggests that seizure disorders are associated with an increased likelihood of intellectual problems. Investigators have explored many potential risk factors. One common predictor variable identified in the literature is age of onset. The relative strength of other seizure-related variables in the prediction of intellectual and cognitive outcome is less clear. The analyses presented in this thesis examine the unique and combined contribution of specific factors (age of seizure onset, duration of illness, laterality of seizure focus, gender and education) to intellectual and cognitive outcome in chronic, unilateral, medication refractory Temporal Lobe Epilepsy (TLE). Adult subjects were selected from a number of epilepsy centers (Cleveland Clinic, Long Island Jewish Medical Center, Mayo Clinic, Epi-Care Center, Yale University, New York University, Medical College of Georgia and University of British Columbia and University of Victoria).;The results indicate that a small portion of the variance in intellectual functioning is accounted for by seizure-related variables, but a much larger amount of the variance is accounted for by the secondary consequences of these factors on the level of education achieved. The combination of seizure-related variables and level of education accounted for a modest amount of the variance in performance on tasks of verbal retrieval and verbal memory. Results are discussed within a developmental context and application to future studies of TLE and other childhood chronic disorders.
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Type
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dissertation
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Source
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PQT Legacy CUNY.xlsx
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degree
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Ph.D.
