Experimental optical-spectroscopy study of: (a) The liquid-glass transition in glycerol. A mode coupling theory analysis. (b) Low-frequency light scattering from powders. Multiple scattering model. (c) Side chain intramolecular hydrogen bond interactions in helical peptides.
Item
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Title
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Experimental optical-spectroscopy study of: (a) The liquid-glass transition in glycerol. A mode coupling theory analysis. (b) Low-frequency light scattering from powders. Multiple scattering model. (c) Side chain intramolecular hydrogen bond interactions in helical peptides.
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Identifier
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AAI9807939
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identifier
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9807939
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Creator
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Hernandez, Joel.
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Contributor
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Advisers: Herman Z. Cummins | Robert Callender
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Date
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1997
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Language
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English
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Publisher
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City University of New York.
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Subject
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Physics, Optics | Physics, Fluid and Plasma | Biophysics, General
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Abstract
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Depolarized light-scattering spectra of the intermediate glass-former glycerol were obtained in the frequency and temperature ranges of 0.4 to 6000 GHz and 173 to 413 K respectively. Analysis of the resulting susceptibility spectra using the asymptotic leading order equations of mode coupling theory (MCT) showed only partial agreement between theory and experiment. However, a recent analysis of our data using a full numerical solution of the MCT equations has been remarkably successful, widening the applicability of the theory to weak network glass-formers and motivating the need to conduct similar tests with strong network glass-formers.;The accidental discovery of a low-frequency band in the light scattering spectrum from a powder of the protein lysozyme lead us to the development of a model for that kind of scattering. Such a model was found to be in very good agreement with our experimental data.;A preliminary infrared absorption experiment on synthesized helical peptides, containing glutamic acid (Glu) amino acid residues spaced periodically along the polypeptide chain, showed evidence for the stabilization of the helical structure of the peptide, by intramolecular hydrogen bonding interactions between the carboxylic acid groups in the side chains of the Glu residues.
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Type
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dissertation
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Source
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PQT Legacy CUNY.xlsx
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degree
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Ph.D.
