Light propagation in paint and prostate human tissues using visible to mid-IR spectroscopy and imaging techniques.
Item
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Title
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Light propagation in paint and prostate human tissues using visible to mid-IR spectroscopy and imaging techniques.
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Identifier
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AAI3144075
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identifier
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3144075
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Creator
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Ali, Jamal Hafiez.
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Contributor
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Adviser: R. R. Alfano
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Date
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2004
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Language
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English
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Publisher
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City University of New York.
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Subject
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Physics, Optics | Physics, Condensed Matter | Physics, Radiation
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Abstract
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The topic of the thesis is to understand the structural and molecular changes in scattering media for bio-medical applications such as animal, and human prostate tissues and non-biomedical applications such as corrosion and cracks beneath paint using steady and time-resolved light spectroscopy and imaging techniques in the visible to mid-IR spectral region. The thesis focuses also on understanding the randomization of coherence and polarization in thin scattering paint medium.;Temporal polarization emission profiles of Fluorescein dye attached to different molecular weight ranging from 4 K to 500 K were measured. Images of an object containing varying molecular weight of Fluorescein dye embedded inside intralipid media were investigated.;The non-invasive spectral polarization difference imaging and the fluorescence polarization difference imaging techniques using Cardio Green dye are introduced in the optical imaging studies to enhance the image quality.;The measured transport length for prostate tissues using time-resolved pulse transmission is ℓtr = 0.86 mm. Four modeling samples of human rectum-membrane-prostate tissue were investigated using the near-infrared spectral polarization imaging technique to detect small foreign objects at different depths inside prostate tissues.;The content of water in cancerous and normal human prostate tissues was shown to be different using near infrared spectroscopy and imaging techniques. The OH stretching vibrational overtone mode at 980 nm, 1195 nm, 1444 nm and other water overtone modes provide key spectroscopic fingerprints to detect non-invasively cancer in prostate tissue.;The value of the transport length (ℓtr) for paint medium obtained from time-resolved pulse transmission, steady state, and degree of polarization measurements is 28mum, 34mu m, and 29mum, respectively. The correlation of time-resolved interference (coherence) and polarization in a scattering thin paint medium has been determined for the first time for the ballistic, snake, and diffusive regions in terms of the mean transport length. The measured linear depolarization length in paint is not in agreement with the current theoretical understanding in scattering media.;The visible to mid-infrared transmission window of paint between 0.5--5.5mu m has been used for the first time to detect corrosion beneath commercial and military paint using spectral polarization imaging and confocal scanning imaging techniques.
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Type
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dissertation
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Source
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PQT Legacy CUNY.xlsx
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degree
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Ph.D.
