Weekend sleep phase delay and the treatment with melatonin.
Item
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Title
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Weekend sleep phase delay and the treatment with melatonin.
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Identifier
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AAI9917716
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identifier
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9917716
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Creator
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Yang, Chien-Ming.
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Contributor
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Adviser: Arthur J. Spielman
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Date
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1999
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Language
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English
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Publisher
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City University of New York.
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Subject
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Health Sciences, Mental Health | Health Sciences, Pharmacology
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Abstract
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Two studies were conducted to address on the common sleep pattern in young adults to stay up late at nights and to sleep-in in the mornings during the weekends. In Experiment 1 the effects of a simulated delayed weekend sleep pattern and its association with individual circadian type were investigated in 30 subjects. The delayed weekend sleep pattern was shown to decrease the level of sleepiness near bedtime on Sunday night and to impair cognitive and mood functioning on Monday morning. Also, circadian type was shown to have limited capacity in predicting the deficits caused by this delayed weekend sleep pattern. In Experimental 2 the effects of exogenous melatonin in counteracting the impacts of the delayed weekend sleep pattern were explored in 10 subjects. Melatonin administration on Sunday late afternoon was demonstrated to effectively advance endogenous melatonin phase and shorten sleep onset latency on Sunday night, and improve mood status on Monday morning. The acute sedating effect of melatonin administration as a potential adverse effect was also discussed.
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Type
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dissertation
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Source
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PQT Legacy CUNY.xlsx
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degree
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Ph.D.
